腹腔镜及开放手术在结直肠癌肝脏转移病灶切除术中的疗效比较

Comparison of laparoscopic and open surgery for resection of liver metastases from colorectal cancer

目的比较腹腔镜及开放手术在结直肠癌肝脏转移病灶切除的临床疗效。方法回顾性分析2009年1月至2011年12月于本院就诊的106例结直肠癌肝脏转移患者临床资料,按手术方案的不同分为观察组(n=54)与对照组(n=52),观察组行腹腔镜手术切除术,对照组给予开腹手术。比较两组手术相关指标、术后1~5年生存情况以及术后不良反应的发生情况。结果观察组术中出血量、手术时间及住院时间均显著少于对照组(均P<0.05)。两组1、3、5年总生存率和无瘤生存率差异均无统计学意义(均P>0.05)。两组术后不良反应总发生率比较差异无统计学意义(P>0.05)。结论腹腔镜手术治疗结直肠癌肝转移安全有效,治疗效果与开放手术相当,利于术后恢复。

Objective To analyze and contrast the application effect of different operative plans in treatment of patients with colorectal liver metastases. Methods Collecting 106 patients with colorectal liver metastases from Jan 2009 to Dec 2011 in our hospital,which were divided into observation group（54 cases） and control group（52 cases） according to different operative plans. The patients in observation group were given laparoscopic surgery treatment, patients in control group were given open surgery treatment. The operation indicator,long-term survival and incidence rate of adverse reaction of three groups were compared. Results The intraoperative bleeding, operation time and hospitalization time of observation group were significantly lower than those of control group（P 〈 0.05）.There was no significant difference in survival time and postoperative complications in two groups（P 〉 0.05）.Conclusion Minimally invasive surgical treatment for colorectal liver metastases is a safe and effective compared to open hepatectomy, which is worthy of clinical promotion.