运动训练对结肠癌患者根治术后营养状况及生活质量的影响

The effects of exercise training on nutritional status and quality of life after radical resection of colon cancer

目的研究运动训练对结肠癌患者根治术后营养状况及生活质量的影响。方法选取本院68例行结肠癌根治手术治疗的患者为研究对象,随机分为观察组与对照组(每组各34例),对照组实施常规术后护理,观察组术后行早期运动训练,比较两组术后肛门排气时间、拔管时间、进食时间、下床时间、住院时间等康复情况,并随访3月比较两组Karnofsky评分差异,比较两组入院时、术后1月、术后3月时血清白蛋白(ALB)、血清前白蛋白(PALB)、转铁蛋白(TRN)、总淋巴细胞计数(TLC)等营养指标,记录两组术后并发症发生率。结果观察组肛门排气时间、拔管时间、进食时间、下床时间、住院时间明显短于对照组(P<0.05),观察组术后Karnofsky评分显著高于对照组(P<0.05);两组入院时营养状况差异无统计学意义(P>0.05),观察组术后1月、3月时ALB、PALB、TRN及TLC水平及营养状况等级均优于对照组(P<0.05);观察组并发症总发生率为2.94%,与对照组(20.59%)比较,差异无统计学意义(P>0.05)。结论早期运动训练有助于缩短结肠癌根治术患者术后康复进程,并可改善营养状态及生活质量,临床应用价值较高。

Objective To investigate the effect of exercise training on nutritional status and quality of life in patients with colon cancer after radical resection.Methods 68 cases of colon cancer patients treated with radical resection in our hospital were selected as our subjects and were randomly divided into observation group and control group with 34 cases in each group. The patients in the control group separately received routine postoperative care and early exercise training after operation.The postoperative anal exhaust time,extubation time, eating time, bed time and hospitalization time were compared between the two groups,all patients were followed up to 3months, and a comparison of the Karnofsky score were undertaken between the two groups. The nutritional indicator including serum albumin（ALB）, serum prealbumin（PALB）, transferrin（TRN） and total lymphocyte count（TLC） at the time of admission, first months and third months after operation were compared between the two groups, and the incidence of postoperative complications in the two groups was recorded. Results The anal exhaust time, extubation time, eating time, out of bed time, hospitalization time of the observation group were significantly lower than those of the control group（P 〈 0.05）.The Karnofsky score of the observation group after operation was significantly higher than that of the control group（P 〈 0.05）.there was no significant difference in nutritional status between the two groups at admission（P 〈 0.05）.The levels of ALB, PALB, TRN, TLC and nutritional status in the observation group were better than those in the control group at the time of first and third months after operation（P 〈 0.05）.The total incidence of complications in the observation group was 2.94%, compared with 20.59% in the control group, the difference was not statistically significant（P 0.05）. Conclusion The early exercise training is helpful for shortening the rehabilitation process of patients with colon cancer after radical operation, improving nutritional status and quality of life, which has high clinical application value.