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长链非编码RNA在妊娠相关疾病中的研究进展 被引量:2

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摘要 长链非编码RNA(long non—coding RNA,lncRNA)是一类长度大于200个核苷酸,不具有编码蛋白质潜能的RNA。不同于微小RNA(microRNA,miRNA)等其他非编码RNA(ncRNA),IncRNA具有相对保守的二级和三级结构,作用方式复杂多样,可在转录、转录后和表观遗传水平调控基因表达,广泛参与机体的生理病理过程。近年来,越来越多的证据表明,lncRNA与多种不良妊娠结局的发生发展密切相关。
出处 《中华围产医学杂志》 CAS CSCD 2017年第10期700-704,共5页 Chinese Journal of Perinatal Medicine
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