人参皂苷Rg3抗肿瘤作用机制的研究新进展

The new advance of reaserch on mechanism of antitumor action of Ginsenoside Rg3

人参皂苷Rg3是从五加科植物人参中提取的重要活性成分之一,其可通过抑制肿瘤细胞增殖,调节机体免疫力,促进肿瘤细胞凋亡,逆转耐药性,减少肿瘤内血管生成,抑制肿瘤细胞的侵袭和转移,联合放、化疗药物减毒增效等发挥抗肿瘤的作用。本文主要对近年来人参皂苷Rg3抗肿瘤的作用机制的研究进展做一综述。

Ginsenoside Rg3 is one of the most active components extracted from Panax ginseng, it can inhibit tumor cell proliferation, regulate the body＇s immunity, promote tumor cell apoptosis, reverse of multidrug resistance, reduce tumor angiogenesis, inhibiting tumor cell invasion and metastasis, toxicity reducing and efficacy enhancing when combined radiation and chemotherapy drugs. In this article, we reviewed the recent progress in the research on the anti-tumor mechanism of Ginsenoside Rg3.