间断性血液透析和持续缓慢低效血液透析在心肾综合征疗效

Clinical effect of IHD and SLED in the treatment of CRS

目的探讨心肾综合征采用持续缓慢低效血液透析(SLED)和间断性血液透析(IHD)治疗的疗效。方法选取62例于2013年5月~2016年5月期间我院接收的心肾综合征患者,按照治疗方式不同分为IHD组(n=31)和SLED组(n=31),观察两组患者的疗效及相关指标在治疗前后的变化。结果两组治疗后的心功能改善疗效比较差异无统计学意义;同时治疗后,两组患者BUN、NT-pro BNP、Scr均较治疗前明显降低,LVEF明显升高,差异具有统计学意义(P<0.05),组间比较差异无统计学意义;此外,IHD组治疗后HR、CVP、PAP较治疗前下降,但组内比较无明显差异性,SLED组治疗后上述指标均较治疗显著下降(P<0.05),且与IHD组比较有明显差异性(P<0.05)。结论 SLED与IHD治疗心肾综合征均能获得较好的疗效,但SLED血流动力学更稳定,具有推广价值。

Objective To explore the clinical effect of SLED(sustained low-efficiency dialysis) and IHD(intermittent hemodialysis) and in the treatment of CRS(cardio-renal syndrome). Methods 62 CRS patients treated from May 2013 to May 2016 in our hospital were selected. The subjects were divided into IHD group and SLED group according to the different therapies, 31 cases each group. The clinical effect and index for two groups were observed. Results After treatment, the cardiac function for two groups was not significantly different; the index of BUN, NT-pro BNP and Scr for two groups were lower than before; the index of LVEF for two groups was significantly higher than before(P<0.05); after treatment, the index of HR, CVP and PAP for two groups were significantly lower than before(P<0.05); the above index for SLED group and IHD group were significantly different(P<0.05). Conclusion Both of the SLED and IHD have a better effect in the treatment of CRS. However, the hemodynamics index based on the SLED is more stable. It is worthy of clinical promotion.