氨甲环酸局部给药结合术后冰敷在单侧全髋关节置换术后患者中的应用效果观察

Observation on the effect of tranexamic acid local administration combined with postoperative ice on patients after unilateral total hip arthroplasty

目的探讨氨甲环酸局部给药结合术后冰敷在单侧全髋关节置换术后患者中的应用效果。方法选取2015年10月~2016年8月赣州市中医院收治的行单侧全髋关节置换术的患者68例,其中35例患者术中应用氨甲环酸进行关节腔内注射,术后对术部行冰敷,将其设定为观察组;33例患者术中未应用氨甲环酸进行关节腔内注射,术后对术部进行冰敷,将其设定为对照组。比较两组术中情况以及术后发生下肢深静脉血栓例数。结果观察组术后可见出血量(151.3±31.8)m L,输血量(399.5±24.7)m L,输血8例,术后24 h血红蛋白(93.2±14.6)g/L,各项指标均优于对照组,差异均具有统计学意义(P<0.05);两组术中出血量差异无统计学意义。结论氨甲环酸局部给药加术后冰敷在全髋关节置换中的应用显著,可使术后出血量明显减少,值得在临床上推广应用。

Objective To investigate the local administration of tranexamic acid combined with postoperative ice in patients with unilateral total hip arthroplasty in the application. Methods 68 underwent unilateral total hip arthroplasty were selected from October 2015 to August 2016 in Ganzhou traditional Chinese medicine hospital for example, intra-articular injection of application of tranexamic acid in 35 patients during operation,postoperative surgery department for ice, which seted for the observation group; 33 patients were not application of tranexamic acid injection in articular cavity after operation of ice in the operation part, which seted for the control group. The intraoperative condition and the number of deep vein thrombosis in lower limbs were compared between the two groups. Results The amount of bleeding after surgery of the observation group(151.3 ±31.8) m L, blood transfusion(399.5 ± 24.7) m L, 8 cases of blood transfusion, postoperative hemoglobin 24 h(93.2 ± 14.6) g/L, the indicators were better than the control group, the differences were statistically significant(P<0.05); no significant amount of bleeding in two groups the difference.Conclusion Topical tranexamic acid combined with postoperative ice in the total hip replacement application significantly, can make the amount of postoperative bleeding was significantly reduced, it is worthy of clinical application.