α受体阻滞剂联合M受体阻滞剂治疗慢性非细菌性前列腺炎的疗效分析

Efficacy analysis of α receptor blocker combined with M receptor blocker in the treatment of chronic nonbacterial prostatitis

目的对慢性非细菌性前列腺炎患者治疗中α受体阻滞剂、M受体阻滞剂联合应用取得的疗效进行分析。方法 100例慢性非细菌性前列腺炎患者,按照治疗方法不同划分为对照组与观察组,各50例。两组患者均行暖水坐浴、规律性生活等常规治疗。对照组患者在常规治疗基础上给予单一M受体阻滞剂治疗,观察组在对照组基础上给予α受体阻滞剂治疗,比较两组患者治疗效果和不良反应发生情况。结果观察组治疗总有效率为66.00%(33/50),高于对照组的42.00%(21/50),差异有统计学意义(P<0.05)。观察组不良反应发生率为2.00%(1/50),与对照组的6.00%(3/50)比较差异无统计学意义(P>0.05)。结论慢性非细菌性前列腺炎患者治疗中,α受体阻滞剂、M受体阻滞剂联合应用取得的疗效显著,且安全性较高,应在临床实践中推广应用。

Objective To analyze the efficacy of α receptor blocker combined with M receptor blocker in the treatment of chronic nonbacterial prostatitis. Methods A total of 100 chronic nonbacterial prostatitis patients were divided by different treatment methods into control group and observation group, with 50 cases in each group. Both groups received conventional therapy of warm water bath and regularity of sex life. The control group also received M receptor blocker for treatment, and the observation group received α receptor blocker on the basis of the control group for treatment. Comparison were made on treatment effect and occurrence of adverse reactions in two groups. Results The observation group had higher total effective rate as 66.00%（33/50） than 42.00%（21/50） in the control group, and their difference was statistically significant（P〈0.05）. The observation group had no statistically significant difference in incidence of adverse reactions as 2.00%（1/50）, comparing with 6.00%（3/50） in the control group（P〉0.05）. Conclusion Combined application of α receptor blocker and M receptor blocker provides remarkable efficacy in treating chronic nonbacterial prostatitis with high safety, and should be promoted and applied in clinical practice.