不同的精液处理方法对体外受精IVF周期结局的影响

The outcomes of different methods to select human spermatozoa for in vitro fertilization

目的比较使用不同精液处理方法对体外受精IVF周期结局的影响。方法回顾性分析2014年1月至2014年12月在我院生殖中心行IVF治疗,选取进行新鲜周期移植的病例,分为密度梯度离心结合上游法组(163例)和单纯上游法分离精子组(75例),对妊娠结局进行比较。结果两组之间的植入率、临床妊娠率、流产率、异位妊娠率等均未见明显差异;结论密度梯度离心结合上游法和单纯上游法分离精子进行IVF的妊娠结局没有明显差异,均是简单安全的分离精子的方法。

Objective：To investigate the outcomes of different methods to select human spermatozoa for in vitro fertilization. Methods：In the present study,a total of 238 cycles（163 of density-gradients combination with swim-up cycles（group A）and 75 of swim-up cycles（group B） of in vitro fertilization（IVF） fresh transfer cycles per formed at our hospital from January 2014 to December 2014 were retrospectively analyzed. Implantation rate,clinical pregnancy rate,miscarriage rate,ectopic pregnancy rate were compared. Results：There were no significant differences between the two groups with respect to implantation rate,clinical pregnancy rate,miscarriage rate,ectopic pregnancy rate. Conclusion：Both density-gradients combination with swim-up methods and swim-up method alone to separate sperm are safe to prepare the sperm for IVF.