某院12847例患者地佐辛注射液临床使用情况调查

Clinical Application Investigation of Dezocine Injection in 12 847 Inpatients in a Hospital

目的:调查地佐辛注射液临床使用情况并对其合理性进行评估。方法:统计分析某院2015年12月~2016年11月住院患者中地佐辛注射液的使用情况,从适应证、用法用量、疗程、联合用药等方面进评价其用药合理性。结果:使用地佐辛的患者共12 847例,年龄0~97岁,平均年龄(49±15.6)岁。11 687例患者是因为手术使用地佐辛注射液,占总比90.97%。使用最多的科室分别是骨科(12.70%)、手外科(10.30%)和肝胆外科(9.39%)。132例患者单次用量超出说明书推荐(1.03%),主要集中在大型手术科室(心外科)。1 042例患者连续用药超过1周(8.11%),主要为肿瘤患者。结论:该院地佐辛注射液临床应用基本合理,但仍存在一些问题,需进一步加强医师培训,提高药物的安全合理应用,降低用药风险。

Objective： To assess the clinical use of dezocine injection. Methods ： The application of dezocine injection in the inpatients during December 2015 and November 2016 in a hospital was statistically analyzed and evaluated from indications, dosage, treatment course and combined drug use, etc. Results： A total of 12 847 patients with the age range of 0-97 and the average age of （49 ±15.6） years old were treated with dezocine injection. The top three departments using dezoeine injection were orthopaedics （ 12.70% ）, hand surgery （ 10.30% ） and liver surgery （9.39%）. Totally 132 patients were with overdose（ 1.03% ）, and mainly in cardiac surgery. The medication course of 1 042 patients was more than one week （ 8.11% ）, which was too long, while most of the patients were with tumor. Conclusion： The clinical use of dezocine injection in the hospital is basically reasonable. However, clinicians still need more training to minimize the risks involved in the process of clinical medicine application.