Pro-ADM、sTREM-1与未足月胎膜早破新生儿感染

Pro-ADM,s TREM-1 and neonatal infection in preterm premature rupture of membranes

近几年研究发现肾上腺髓质素前体及可溶髓样细胞表达触发受体-1可明确感染诊断,判断感染的严重程度,预测感染预后。本文将就肾上腺髓质素前体、可溶髓样细胞表达触发受体-1及未足月胎膜早破新生儿感染相关问题进行综述。

In recent years,preterm premature rupture of membranes gradually attracts attention. Due to the relation ship between premature rupture of membranes and infection,it is necessary to find not only prediction of the occurrence of maternalpreterm premature rupture of membranes, but also early signs of neonatal infection and its extent. Recent studies have discovered that adrenomedullin precursor and soluble myeloid cell expression trigger receptor1 （sTREM-1） can help make definitive diagnosis of infection, as well as determine the severity of infection and predict the prognosis. This article will review studies and progress on adrenomedullin precursor,soluble myeloid cell expression triggering receptor1 and pre term premature rupture of membranes,as well as review related issues.