整合素的基因表达调控

Regulation of integrin gene expression

整合素是一类重要的细胞表面分子,参与细胞增殖、分化、黏附和迁移等过程,在多种病理过程中发挥重要作用。近年来,关于整合素调控研究的不断深入及在肿瘤、组织纤维化和伤口愈合等治疗中发挥的重要作用不断被挖掘,整合素逐渐成为疾病诊断和治疗的新靶点。本文将对整合素的基因表达调控进行综述。

Integrin is a class of important cell surface molecules involved in cell proliferation,differentiation,adhesion and migration processes,which play an important role in a variety of pathological processes.In recent years,with the research in integrin regulation and the treatment of tumor,tissue fibrosis,and other fields,integrin has gradually become a new target in the diagnosis and treatment of diseases.In this article,we provide a summary on the advances of the regulation of integrin gene expression.