摘要
目的:观察艾滋病患者肺气虚弱证和肺脾气虚证与T淋巴细胞之间的相关性。方法:选取艾滋病肺气虚弱证患者34例,肺脾气虚证患者68例作为研究对象,运用流式细胞仪检测不同证型患者T淋巴细胞亚群水平,分析中医证型与T淋巴细胞亚群的相关性。结果:肺气虚弱证患者CD_3^+T淋巴细胞为(1 547.12±807.909)mm^(-3),肺脾气虚证患者CD_3^+T淋巴细胞为(1 213.09±580.928)mm^(-3),两组比较,差异有统计学意义(P=0.019<0.05);肺气虚弱证患者CD_8^+T淋巴细胞为(1 090.59±632.818)mm^(-3),肺脾气虚证患者CD_8^+T淋巴细胞为(860.06±456.800)mm^(-3),两组比较,差异有统计学意义(P=0.038<0.05);CD_4^+方面,肺脾气虚证患者的平均秩次为47.13,肺气虚弱证患者的平均秩次为60.24,两组比较,差异有统计学意义(P=0.035<0.05);CD_4^+/CD_8^+方面,肺脾气虚证患者平均秩次为50.43,肺气虚弱证患者平均秩次为53.65,两组比较,差异无统计学意义(P=0.604>0.05)。结论:艾滋病肺脾气虚证患者淋巴细胞下降更显著,免疫功能损伤更严重,更容易出现机会性感染。
Objective: To observe AIDS pulmonary Qi weakness and pulmonary-spleen deficiency and its correlation with T lymphocytes. Methods: Through collecting information table of syndromes of lung Qi weakness( 34 cases) and lung-spleen Qi deficiency( 68 cases),using flow cytometry instrument detection of T lymphocyte subsets,using SPSS statistical AIDS pulmonary Qi weakness and pulmonary-spleen Qi deficiency and its correlation with T lymphocyte subsets. Results: Qi deficiency in patients with CD_3~+T lymphocytes( 1 547. 12 ± 807. 909) mm-3,CD_3~+T lymphocytes with lung and spleen Qi deficiency syndrome was( 1 213. 09 ±580. 928) mm^(-3),the difference was statistically significant( P = 0. 019 〈0. 05); Qi deficiency in patients with CD_8~+T lymphocytes( 1 090. 59 ± 632. 818) mm^(-3),CD_8~+T lymphocytes in patients with lung-spleen Qi deficiency syndrome for( 860. 06 ±456. 800) mm-3,between the two groups,the difference was statistically significant( P = 0. 038〈 0. 05); in CD_4~+,patients with lung-spleen Qi deficiency syndrome,the mean rank of 47. 13,patients with pulmonary Qi deficiency syndrome of the average rank was 60. 24,the difference was statistically significant( P = 0. 035 〈0. 05); in CD_4~+/CD_8~+,lung spleen Qi deficiency syndrome with the average rank was 50. 43 in patients with pulmonary Qi deficiency syndrome,the average rank was 53. 65,the difference was not statistically significant( P = 0. 604 〉0. 05). Conclusion: The lymphocytes in HIV/AIDS patients of lung spleen Qi deficiency syndrome decreasing more significantly,the immune function damage is more serious,more vulnerable to opportunistic infections.
出处
《中医学报》
CAS
2017年第10期1811-1813,共3页
Acta Chinese Medicine
关键词
艾滋病
肺气虚弱证
肺脾气虚证
T淋巴细胞
中医证型
AIDS
lung Qi weakness syndrome
Qi deficiency of lung and spleen syndrome
T lymphocyte
TCM syndrome