基因工程重组乳酸菌研究进展

Advances in genetic engineering of recombinant Lactic acid bacteria

乳酸菌是人和动物肠道内常见的益生菌,具有提供营养、改善胃肠道功能、提高免疫力、抗菌等作用,随着基因工程技术的发展,选择乳酸菌作为载体传递系统,在细菌、病毒、肿瘤、寄生虫等领域构建了一系列重组乳酸菌。本文就基因工程重组乳酸菌的制备及防治效果作一综述。

Lactic acid bacteriaare common probiotic organisms in the intestines of animals and humans,and these bacteria supply nutrition,improve gastrointestinal function,improve immunity,and combat microbes.As genetic engineering has advanced,Lactic acid bacteriahave been chosen as a vector for delivery of different substances.Recombinant Lactic acid bacteriahave been created in areas such as virology,bacteriology,parasitology,and oncology.This paper reviews the creation of recombinant Lactic acid bacteriaand their effectiveness at protecting the intestines.