脑梗塞病人血清微量元素测定分析及临床意义

Determination and clinical significance of the content of serum trace elements in patients with cerebral infarction

目的 研究血清微量元素的变化与脑梗塞的关系。方法 采用原子吸收光谱法对 72例脑梗塞患者和 4 6例正常人的血清Sr、Ni、Co、Cr、Fe、Mn、Mo、Cd、Cu、Zn、Ca、Mg、Se等微量元素含量进行了测定。 结果 脑梗塞组血清Sr、Mn和Cu/Zn、Sr/Se、Mn/Se比值显著高于对照组 (P <0 0 1) ,Mo、Zn、Ca、Mg、Se显著低于对照组 (P <0 0 1) ,而Ni、Co、Cr、Cd、Fe等与对照组无显著性差异 (P >0 0 5 )。结论 Zn、Sr、Mn、Mo、Ca、Mg含量及Cu/Zn、Sr/Se。

Objective To study the relationship between the change of serum trace elements and cerebral infarction.Methods The content of Sr,Ni,Co,Cr,Fe,Mn,Mo,Cd,Cu,Zn,Ca,Mg and Se in serum from 72 patients with cerebral infarction, and the control group were determined by atomic absorption spectrometry.Results The patients had markedly higher contents of Sr,Mn and Cu/Zn, Sr/Se,Mn/Se value than the control group( P <0 01),and had markedly lower contents of Zn,Mo,Ca,Mg,Se than the control group( P <0 01),and contents of Ni,Co,Cr,Cd,Fe from the patients had no significant difference with the control group( P >0 05).Conclusion The obtained results supported that the contents of Zn,Sr,Mn,Mo,Ca,Mg and Cu/Zn, Sr/Se,Mn/Se value had close relationship with cerebral infarction.