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瑞舒伐他汀对冠状动脉性心脏病合并高脂血症患者血脂、hs-CRP及MFG-E8水平表达的影响 被引量:1

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摘要 目的:观察瑞舒伐他汀对冠状动脉性心脏病(CHD)合并高脂血症患者血脂、高敏C反应蛋白(hs-CRP)及乳脂肪球表皮生长因子8蛋白(MFG-E8)水平表达的影响。方法:选取我院CHD合并高脂血症患者96例,采用随机数字表法分组,各48例。对照组予以常规治疗,观察组在对照组基础上予以瑞舒伐他汀治疗。对比两组治疗前后血脂[低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、三酰甘油(TG)、总胆固醇(TC)]、hs-CRP及MFG-E8水平。结果:观察组治疗后LDL-C、TG、TG水平高于对照组,HDL-C水平低于对照组,差异有统计学意义(P<0.05);观察组治疗后hs-CRP低于对照组,MFG-E8水平高于对照组,差异有统计学意义(P<0.05)。结论:瑞舒伐他汀可有效调节血脂,降低hs-CRP水平,提高MFG-E8水平,有助于及时清除凋亡细胞,减轻炎症反应。
作者 苏宁
出处 《北方药学》 2017年第11期127-128,共2页 Journal of North Pharmacy
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