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阿霉素联合阿莫西林钠克拉维酸钾对人胃癌AGS细胞的作用

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摘要 目的:探讨化疗联合阿莫西林钠克拉维酸钾对胃癌AGS细胞的影响。方法:应用阿莫西林钠克拉维酸钾及其分别联合阿霉素(ADM)处理AGS细胞,应用MTT、Transwell模型,流式细胞术检测细胞增殖、迁移能力及细胞凋亡。结果:阿莫西林钠克拉维酸钾可呈浓度和时间依赖性抑制胃癌AGS细胞的增殖、迁移并促其凋亡(P均<0.05)。阿莫西林钠克拉维酸钾可协同化疗药物抑制胃癌AGS细胞的增殖、迁移并促其凋亡(P均<0.05)。结论:阿莫西林钠克拉维酸钾可抑制胃癌AGS细胞的增殖、迁移并促其凋亡,并与阿霉素联用具有协同作用。
出处 《北方药学》 2017年第11期151-151,162,共2页 Journal of North Pharmacy
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