2015年重庆市结直肠肛门癌发病与死亡现状分析

Analysis on incidence and mortality of colorectal cancer in Chongqing municipality,2015

目的:了解重庆市结直肠肛门癌发病死亡现状,为开展结直肠肛门癌防治工作提供建议。方法:采用国际疾病分类与国际肿瘤学分类收集整理2015年重庆市11个肿瘤登记点报告的结直肠肛门癌(C18-C21)新发肿瘤病例资料。数据经SPSS19.0统计分析发病率、死亡率、中国人口标化发病率与死亡率、世界人口标化发病率与死亡率与构成比。不同性别、地区间发病率与死亡率的比较采用卡方检验,年龄别发病率与死亡率趋势分析采用趋势卡方检验,检验水准α=0.05。结果:2015年结直肠肛门癌发病率居所有恶性肿瘤的第2位,占所有报告恶性肿瘤的10.51%,发病率、ASIRC与ASIRW分别为28.32/105、17.57/105、19.32/105,发病率男性(32.80/105)高于女性(23.74/105),差异有统计学意义(χ~2=8.572,P=0.003)。截缩率为25.77/105,累积率为2.10%,累积危险度为2.08%。死亡率、ASMRC与ASMRW分别为13.95/105、8.02/105、9.33/105,死亡率男性高于女性(χ~2=9.410,P=0.002),城市高于农村(χ~2=6.378,P=0.012),截缩率为9.38/105,累积率与累积危险度分别为0.89%与0.88%。结直肠肛门癌发病率与死亡率均随年龄的增长而上升,趋势检验差异有统计学意义(χ~2值分别为14.533与11.398,P值分别为0.000和0.001),发病率40岁后呈快速上升趋势,死亡率50岁后呈快速上升。结论:重庆市结直肠肛门癌发病率与死亡率均较高,应重视结直肠肛门的三级预防工作。

Objective：To understand the incidence and mortality of colorectal cancer in Chongqing and to provide the suggestion for colorectal cancer prevention and control. Methods ： Colorectal cancer cases （ICD- 10 code： C 18-C21 ） from 11 cancer registration sites were collected and sorted by the international category of disease（ICD-10） and the international category of tumor（ICD-O-3）. The data were analyzed to calculate the incidence,mortality and age-specific standardized incidence rate and mortality rate by Chinese standard population（ASIRC/ASMRC） and World standard population（ASIRW/ASMRW） and proportion by SPSS 19.0. The difference of the incidence and mortality of colorectal cancer between the male and female,urban and rural area was compared by Chi-square test. The trend of colorectal cancer with age was analyzed by trend Chi-square test（a=0.05）. Results ：The incidence of colorectal cancer ranked the second of all cancers in 2015 in Chongqing,which accounted for 10.51% of all cancers. The incidence,ASIRC, ASIRW of colorectal cancer was 28.32/10^5,17.57/10^5 and 19.32/105 respectively in 2015. The incidence of colorectal cancer among male residents （32.80/10^5） was higher than that among female residents （23.74/10^5） significantly （X2=8.572, P=0.003）. The truncated rate of age 35-64, cumulative rate and cumulative risk of colorectal cancer incidence were 25.77/105, 2.10% and 2.08% respectively. The mortality, ASMRC and ASMRW of colorectal cancer were 13.95/10^5,8.02/10^5 and 9.33/105 respectively in 2015. The mortality of colorectal cancer among male residents was higher than that among female residents significantly （X2=9.410,P=0.002）. The mortality of colorectal cancer in urban area was higher than that in rural area significantly（x2=6.378,P=0.012）. The truncated rate of age 35- 64, cumulative rate and cumulative risk of colorectal cancer mortality were 9.38/105, 0.89% and 0.88 % respectively. The incidence and mortality of colorectal cancer increased significantly with the age（x2=14.533, P=0.000 ;x2=11.398, P=0.001 ）. The incidence of col- orectal cancer increased rapidly after 40 years old and its mortality increased rapidly after 50 years old. Conclusion：The incidence andmortality of colorectal cancer is high in Chongqing munici- pality. Great importance should be attached to tertiary prevention for colorectal cancer.