摘要
建立了一种快速检测聚碳酸酯(PC)桶中对叔丁基苯酚、对苯二甲酰氯和间苯二甲酰氯迁移量的高效液相色谱分析方法。采用ZORBAX SB-C_(18)作为色谱柱,对流动相的组成和洗脱方式、检测波长等参数进行优化。结果表明:以甲醇和水为流动相,梯度洗脱,柱温30℃,可使得对叔丁基苯酚、对苯二甲酰氯和间苯二甲酰氯在10 min内实现分离;在优化条件下,对叔丁基苯酚、对苯二甲酰氯、间苯二甲酰氯在0.1~10.0μg/ml浓度范围内呈良好的线性关系,相关系数为0.999,方法的检出限(LOD,S/N=3)为0.01~0.0.3μg/ml,定量限(LOQ,S/N=10)为0.05~0.1μg/ml。该方法分离效果良好,准确可靠,方便快捷,可用于PC桶中对叔丁基苯酚、对苯二甲酰氯和间苯二甲酰氯的快速检测。
A high performance liquid chromatographic method was developed for the rapid detection of the migration of tert-butylphenol, terephthaloyl chloride and isophthaloyl dichloride in polycarbonate（PC） barrel. ZORBAX SB-C18 was used as the chromatographic column to optimize the composition, elution mode and detection wave length of the mobile phase. The results demonstrate that： with methanol and water as the mobile phase, gradient elution, column temperature of 30℃, can make tert-butylphenol, terephthaloyl chloride and isophthaloyl dichloride in 10 min separation. Under the optimized experimental conditions, the calibration curves of tert-butylphenol, terephthaloyl chloride and isophthaloyl dichloride were linear in the range of 0.1~10.0 μg/ml with correlation coefficients more than 0.999. The limits of detection（LOD, S/N=3） were in the range of 0.01~0.03 μg/ml. The limits of quantitation（LOQ, S/N=10） were in the range of 0.05~0.1 μg/ml. The established method has the advantages of good separation, high accurancy, high recovery, convenience and rapidness, and could be used for the analysis of tert-butylphenol, terephthaloyl chloride and isophthaloyl dichloride in PC barrel.
出处
《塑料科技》
CAS
北大核心
2017年第11期95-98,共4页
Plastics Science and Technology
基金
浙江省质量技术监督系统科研计划项目(20170238)
