胎儿系统超声检查在产科胎儿畸形筛查中的应用价值

Value of Fetal Anatomic Ultrasonography in Obstetric Screening for Fetal Malformations

目的探讨产科胎儿畸形筛查中胎儿系统超声检查的临床应用价值。方法将824例行产前检查的中、晚孕期孕妇按随机数字表法分为2组:观察组412例行胎儿系统超声检查,对照组412例行常规产科超声检查。比较2组孕妇胎儿畸形检出率与漏诊率。结果观察组检出胎儿畸形13例,检出率为3.09%;对照组检出3例,检出率为0.73%,观察组检出率显著高于对照组,差异有统计学意义(χ~2=6.374,P=0.012)。观察组最终证实胎儿畸形14例,漏诊1例,漏诊率为7.14%;对照组最终证实胎儿畸形12例,漏诊9例,漏诊率为75.00%,观察组漏诊率明显低于对照组,差异有统计学意义(χ~2=12.571,P=0.000)。结论胎儿系统超声检查用于产科胎儿畸形筛查,可有效提高畸形检出率,减少漏诊,对改善人口素质,降低围产儿死亡率有重要意义。

Objective To investigate the clinical value of fetal anatomic ultrasonography in obstetric screening for fetal malformations.Methods A total of 824 pregnant women in the middle and late pregnancy were randomly assigned to receive either fetal anatomic ultrasonography（observation group,n=412）or routine obstetric ultrasonography（control group,n=412）.The detection rate and missed diagnosis rate of fetal malformations were compared between the two groups.Results The detection rate of fetal malformations in observation group（3.09%,13cases）was significantly higher than that in control group（0.73%,3cases）（χ~2=6.374,P=0.012）.Fourteen cases were finally diagnosed with fetal malformations in observation group,and 12 cases in control group.The missed diagnosis rate in observation group（7.14%,1case）was significantly lower than that in control group（75.00%,9cases）（χ~2=12.571,P=0.000）.Conclusion Fetal anatomic ultrasonography can increase the detection rate of fetal malformations and reduce the rate of missed diagnosis.Therefore,the application of fetal anatomic ultrasonography in obstetric screening is of great significance for improving the quality of population and reducing the rate of perinatal mortality.