无创正压通气治疗重症慢性阻塞性肺疾病呼吸衰竭疗效观察

Study of Curative Effect of Noninvasive Positive Pressure Ventilation in the Treatment of Severe Chronic Obstructive Pulmonary Disease with Respiratory Failure

目的探究在重症慢性阻塞性肺疾病呼吸衰竭患者的临床治疗过程中,无创正压通气对于患者的治疗效果,并评价其安全性。方法将我院2014年3月至2016年5月期间收治的98例重症慢性阻塞性肺疾病呼吸衰竭患者作为研究对象,随机分为观察组和对照组各49例,对照组给予常规吸氧、祛痰、平喘解痉等治疗,观察组在对照组治疗基础上给予无创通气治疗。比较两组疗效。结果观察组总有效率93.8%,显著高于对照组(81.6%),差异有统计学意义(P<0.05);观察组患者血气分析结果的改善程度显著优于对照组,差异有统计学意义(P<0.05);观察组患者的肺功能参数的改善幅度明显优于对照组,差异有统计学意义(P<0.05)。结论无创正压通气治疗能显著改善重症慢性阻塞性肺疾病呼吸衰竭患者症状,改善患者肺功能,值得推广。

Objective To investigate the efficacy of noninvasive positive pressure ventilation in the treatment of severe chronic obstructive pulmonary disease（COPD） patients with respiratory failure,and to evaluate its safety. Methods 98 cases of patients with severe chronic obstructive pulmonary disease and respiratory failureadmitted in our hospital between March 2014 and May 2016 were selected and randomly divided into the experimental group and the control group,each with 49 cases. The control group received routine oxygen inhalation,expectorant,antiasthmatic,antispasmodic and other treatment,while the experimental group was given non-invasive ventilation treatment on the basis of the treatment of the control group. The efficacy of the two groups was compared. Results The total effective rate of the experimental group was 93. 8%,significantly higher than that of the control group（81. 6%）,and the difference was statistically significant（P〈0. 05）; The improvement of blood gas analysis in the experimental group was significantly better than that in the control group,statistically significant（P〈 0. 05）; The improvement of pulmonary function parameters in the experimental group was obviously better than that in the control group,statistically significant（P〈0. 05）.Conclusion Noninvasive positive pressure ventilation can significantly improve the symptoms of respiratory failure in patients with severe chronic obstructive pulmonary disease and improve the pulmonary function of patients,which is worth of being popularized.