降钙素原联合C反应蛋白检测在血流感染早期诊断中的价值分析

Value of Procalcitonin Combined with C-reactive Protein Detection in the Early Diagnosis of Bloodstream Infection

目的:分析降钙素原(CRP)联合C反应蛋白(PCT)检测在血流感染早期诊断中的价值。方法:选取2016年5月~2017年1月某院接收的血流感染患者71例,将其作为试验组,同时选同期其他局部感染患者70例,将其作为参照组,对两组患者均行降钙素原联合C反应蛋白检测,检测血清CRP、PCT水平,之后做菌种鉴定与血培养,同时对比两组诊断效果。结果:试验组血清CRP、PCT水平检测阳性率为70.42%、97.18%,均比参照组的8.57%、88.57%高,差异较明显(P<0.05);71例血流感染患者中,48例革兰阴性菌感染患者血清PCT水平比23例革兰阳性菌感染患者更高(P<0.05)。结论:临床对血流感染患者开展早期诊断工作时,予以CRP联合PCT检测的效果较显著,可明显提升PCT诊断评判水平,值得推荐。

Objective:To analyze the value of procalcitonin(CRP)combined with C-reactive protein(PCT)in the early diagnosis of bloodstream infection.Methods:71 patients with bloodstream infection treated in a hospital from May 2017 to January 2017 were selected as experimental group and another 70 patients with other local infections were selected as reference group.The two groups were given procalcitonin combined with C reactive protein test,the levels of serum CRP and PCT were detected,and then the strains were identified and cultured with blood culture.At the same time,the effect of 2 groups was observed and compared.Results:The positive rate of serum CRP and PCT was 70.42%and 97.18%in the experimental group,which was significantly higher than that in the control group(8.57% and 88.57%,P<0.05).Among the 71 cases of bloodstream infection,the serum PCT levels in 48 patients with gram-negative bacterial infection was higher than that in 23 patients with gram-positive bacterial infection(P<0.05).Conclusion:In the early stage of diagnosis of bloodstream infection,the effect of CRP combined with PCT detection is obvious,which can obviously improve the level of PCT diagnosis and judgment.