COPD急性发作期患者早期SIRS评分及NT-proBNP与患者病死率的相关性研究

The correlation between early SIRS score and NT-pro BNP and mortality of patients with COPD acute episodes were studied

目的探讨慢性阻塞性肺疾病(COPD)患者急性发作期的SIRS评分及N末端B型脑钠肽(NT-pro BNP)水平与患者肺功能的关系以及对患者预后的影响。方法回顾性分析COPD患者缓解期肺功能的情况进行分级,在患者急性发作期统计SIRS评分并检测NT-pro BNP水平后进行统计分析。结果 COPD患者肺功能越差急性发作期SIRS评分及NT-pro BNP水平越高,而肺功能三级和四级患者早期SIRS评分及NT-pro BNP水平对于病死率有较高的灵敏度和特异度。结论早期SIRS评分及NT-pro BNP水平对COPD患者急性发作期的预后判断具有一定临床意义,肺功能较差的患者早期SIRS评分及NT-pro BNP水平对于病死率的判断有较高的灵敏度和特异度。

Objective To investigate the SIRS score of patients with chronic obstructive pulmonary disease（ COPD） and the relationship between NT-proBNP values,patients＇ lung function,the prognosis of patients with COPD. Methods According to the condition of the patients＇ remission of lung function,the statistical analysis was carried out on the statistical SIRS score and NT-proBNP number of the patients during the acute attack period. Results The worse lung function were in the acute phase SIRS,and the higher was the NT-proBNP. For patients with lung function of level 3 and level 4 patients,early SIRS score and the NT-proBNP has higher sensitivity and specificity on mortality evaluation. Conclusion The early SIRS score,the NT-proBNP level has a certain clinical significance in the prognostic judgment of COPD patients in acute phase. For patients with poor lung function,early SIRS score and the NT-proBNP level has higher sensitivity and specificity in the judgment for patient mortality evaluation.