坦索罗辛联合黄体酮穴位注射治疗输尿管下段结石的临床应用研究

Clinical application of tamsulosin combined with progesterone acupoint injection in the treatment of lower ureteral calculi

目的研究坦索罗辛联合黄体酮穴位注射治疗输尿管下段结石的临床疗效。方法将2016年1月~2017年1月对我院收治的80例输尿管下段结石患者随机分为两组,每组40例。对照组仅予坦索罗辛缓释片;观察组采用坦索罗辛联合黄体酮穴位注射法。对比分析两组的结石排除率、排出时间、肾绞痛发生情况、疼痛缓解时间、治疗效果和并发症等的差异。结果观察组的治疗有效率为95%,明显高于对照组的80%,差异具有统计学意义(P<0.05)。观察组的结石排除率为87.5%,明显高于对照组的67.5%,差异具有统计学意义(P<0.05)。观察组的结石排出时间、肾绞痛发生率和疼痛缓解时间显著低于对照组,差异具有统计学意义(P<0.05)。观察组的并发症发生情况与对照组差异无统计学意义(P>0.05)。结论坦索罗辛联合黄体酮穴位注射治疗输尿管下段结石疗效显著,在临床中值得推广应用。

Objective To study the clinical efficacy of tamsulosin combined with progesterone acupoint injection in the treatment of lower ureteral calculi. Methods 80 patients with lower ureteral calculi admitted in our hospital from January 2016 to January 2017 were randomly divided into two groups, with 40 cases in each group. The control group was treated with tamsulosin sustained-release tablets.The observation group was treated with tamsulosin and progesterone acupoint injection.The stone excretion rate,discharge time,the occurrence of renal colic,pain relief time, treatment effect and adverse situation such as complications between the two groups were compared. Results The effective rate was95% in the observation group, higher than that in the control group（80%）, and the difference was statistically significant（P〈0.05）. The stone excretion rate of the observation group was 87.5%, which was significantly higher than that of the control group（67.5%）, and the difference was statistically significant（P〈0.05）. The stone excretion time, the incidence of renal colic and pain relief time were significantly lower in the observation group than those in the control group, and the difference was significant（P〈0.05）. There was no significant difference in the incidence of complications between the observation group and the control group（P〈0.05）. Conclusion Tamsulosin combined with progesterone acupoint injection for the treatment of lower ureteral calculi is effective and worthy of promotion in clinical practice.