罗非鱼无乳链球菌传播途径与逃避宿主免疫防御策略

Transmission routes of Streptococcus agalactiae and the strategy of immune evasion in tilapia

罗非鱼是我国重要的养殖鱼类之一,近年来频繁暴发的链球菌病严重影响了我国罗非鱼养殖业的健康发展。无乳链球菌是罗非鱼链球菌病的主要病原之一,阐明其感染机制和免疫逃避机制,对预防与治疗该病至关重要。对鱼源无乳链球菌的侵染途径、肠道的定植策略以及逃避宿主免疫监视机制等方面的研究成果进行综述,为深入研究无乳链球菌与宿主之间的相互作用提供参考,为罗非鱼链球菌病的综合防控奠定理论基础。

Tilapia is one of the most important aquaculture fish in China. In recent years,the tilapia aquaculture industry was seriously damaged by the frequently outbreak of streptococcicosis. In this review,the transmission routes of Streptococcus agalactiae,intestinal colonization and the mechanisms of immune evasion were discussed aim to provide useful idea for further research on pathogenesis of S. agalactiae and the prophylaxis and therapy for streptococcicosis of tilapia.