浅谈NCPAP序贯高流量鼻导管湿化氧疗治疗新生儿呼吸窘迫综合征效果观察

Effect of NCPAP Sequential High Flow Nasal Oxygen Therapy on Neonatal Respiratory Distress Syndrome

目的:探讨NCPAP序贯高流量鼻导管湿化氧疗治疗新生儿呼吸窘迫综合征的临床效果。方法:选取2015年10月至2016年7月我院收治的新生儿呼吸窘迫综合征患儿68例作为此次研究对象,随机将所有患儿分为两组,对照组和观察组各有34例患儿,对照组接受NCPAP治疗,观察组接受NCPAP结合HHFNC治疗,对两组患者临床效果予以比较。结果:两组患儿治疗后的Sp O2、Pa O2以及Pa CO2水平比较无统计学差异(P>0.05);观察组患儿并发症发生率是20.6%,对照组患儿并发症发生率是52.9%,组间并发症发生情况比较存在显著性差异(P<0.05)。结论:新生儿呼吸窘迫综合征运用NCPAP序贯高流量鼻导管湿化氧疗治疗具有显著临床效果,能够明显减少患儿并发症,安全性高,值得临床大力推广。

Objective： To explore the clinical effect of NC- PAP sequential high flow nasal catheter oxygen therapy in the treatment of neonatal respiratory distress syndrome. Methods： 68 cases of neonatal respiratory distress syndrome treated in our hospital from October 2015 to July 2016 were selected as the re- search object, All the children can be divided into two groups at random, control group and observation group with 34 cases, The control group NCPAP therapy, observation group received NC- PAP HHFNC treatment, Comparison of two groups of patients with clinical effect. Results： There was no significant difference in SpO2, PaO2 and PaCO2 between the two groups （P〉 0.05）. The complication rate of observation group was 20.6%, the control group was 52.9%, the complication rate was, there was signifi- cant difference between the two groups （P 〈 0.05）. Conclusion： The application of NCPAP sequential high flow nasal catheter oxygen therapy in neonatal respiratory distress syndrome has a significant clinical effect, and can significantly reduce the com- plications of patients with high safety, it is worthy of clinical ap- plication.