超临界流体中药物/聚合物微粒化技术的研究进展

Research progress of micronization technology on durg/polymer in supercritical fluid

用超临界流体技术制备的微粒克服了粒径尺寸较大、粒径尺寸分布不均匀以及有机溶剂残留等问题。介绍了几种超临界流体技术的工作原理,综述了近几年的应用情况,并对超临界流体技术的研究发展方向与应用前景进行了展望。

The methods of preparing microparticles by supercritical fluid technology can overcome these problems which are large particle size,uneven distribution of particle size and residual organic solvent.The working principles of several supercritical fluid technologies were introduced,and the application of supercritical fluid technologies in recent years were summarized.The further research and application of the supercritical fluid technologies were prospected.