中药超微粉质量标准制定方法的研究进展

The research progress of Chinese medicine superfine powder quality standard

查阅、分析、总结近年有关中药超微粉质量控制研究的相关文献,咨询生产厂家关于破壁饮片质量控制与评价的方法。中药超微粉的质量控制与评价方法主要有基因鉴别技术、粒度测定、细胞破壁率检查等,集中在定性鉴别和定量分析两个方面。定性鉴别主要有薄层色谱法、HPLC指纹图谱法和DNA分子鉴定技术法等,含量测定多用高效液相色谱法等。目前中药破壁饮片的质量控制和评价研究取得一定的进展,但还不够完善,质量控制与评价的方法和技术有待于进一步的探索和提高。

This paper consults, analyses and summarizes the literatures about superfine powder quality control study of Chi-nese medicine. The quality control and assessment methods are mainly gene identification, granulometry and cell - wall break-ing ratio inspection, which are divided into qualitative discrimination and quantitative analysis. Qualitative discriminations are mainly thin layer chromatography, HPLC fingerprint chromatogram method and DNA Molecular identification. Quantitative measurement mainly applies high performance liquid chromatography. For now, quality control and assessment research of Chinese medicine broken cell slices gain some progress, but they still need further exploration and improvement.