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重度侵袭性牙周炎牙周基础治疗后对TNF-α、IL-4水平的影响 被引量:1

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摘要 目的探讨重度侵袭性牙周炎牙周基础治疗后对TNF-α、IL-4水平的影响。方法选取我院收治的重度侵袭性牙周炎患者120例牙周基础治疗作为研究对象。比较治疗前后患者血清、龈沟液TNF-α、IL-4水平及牙周指标的差异。结果治疗后患者血清TNF-α、IL-4水平稍低于治疗前,差异无统计学意义(P>0.05);治疗后患者龈沟液TNF-α水平显著低于治疗前,而IL-4水平显著高于治疗前,差异有统计学意义(P<0.05);治疗后患者牙周探诊深度(PD)、探诊出血指数(BOP)、附着水平(AL)显著低于治疗前,差异有统计学意义(P<0.05)。结论重度侵袭性牙周炎牙周基础治疗后效果显著,其可降低龈沟液TNF-α水平,升高IL-4水平,改善牙周功能,值得临床选择。
作者 方海林
出处 《全科口腔医学电子杂志》 2016年第10期78-79,共2页 Electronic Journal of General Stomatology
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