30例急性淋巴细胞白血病患儿化疗及休疗期间的膳食调查

Dietary Survey of 30 Patients with Acute Lymphoblastic Leukemia During Chemotherapy and Rest

目的:通过膳食调查了解饮食对急性淋巴细胞白血病(ALL)患儿营养状况的影响,为患儿是否需要营养干预提供依据。方法:选取有陪住家长的30例ALL住院患儿,调查并计算住院和休疗期间各3d的膳食摄入量;监测入院初、返院后的体质量和生化指标及消化系统不良反应。结果:2~5岁患儿院内膳食的总能量和蛋白质摄入量均低于休疗期(P<0.05);患儿入院初的前白蛋白和血红蛋白低于返院后(P<0.05),白蛋白变化不大(P=0.194);入院初1例超重、1例营养不良,28例正常;返院时1例超重、3例营养不良,26例正常;27例(90%)患儿分别出现恶心、呕吐、口腔溃疡等各种不同程度的不良反应。结论:化疗危害ALL患儿的营养状况,应由营养师与临床医生配合积极予以营养干预。

Objective To investigate the effect of diet on the nutritional status of children with acute lymphoblastic leukemia（ ALL）,and to provide evidence for nutritional intervention. Method We selected accompany parents of 30 cases of hospitalized children with ALL,survey and calculation of hospitalization and hugh therapy during the 3 days of dietary intake,and monitor early admission and back to the hospital after the body quality and biochemical index and digestive system adverse reactions. Result 2 ~ 5 years old children in hospital dietary total energy and protein intakes were lower than hugh therapy（ P 〈 0. 05）. Children admitted to hospital at the beginning of the pre albumin and hemoglobin less than the return to the hospital（ P 〈 0. 05） and albumin did not change significantly. Early admission 1 cases of overweight,1 cases of malnutrition,28 cases of normal. Back to the hospital 1 overweight people,3 people malnutrition,26 cases of normal. Totally 27 cases（ 90%） patients were nausea,vomiting,ulcers in the mouth with a variety of different levels of adverse reactions.Conclusion The nutritional status of ALL patients with chemotherapy should be combined with the doctor to actively nutrition intervention.