循经刮痧配合氯雷他定治疗持续性变应性鼻炎的临床研究

Clinical Study on the Treatment of Persistent Allergic Rhinitis by Scraping Therapy Along Meridian Combined with Loratadine

目的探讨循经刮痧配合氯雷他定治疗持续性变应性鼻炎(PAR)肺经伏热证的临床疗效。方法选取2015年3月至2016年9月南京中医药大学附属医院耳鼻咽喉科门诊收治的PAR属肺经伏热证患者60例,随机分为氯雷他定对照组和刮痧配合氯雷他定治疗组,每组各30例,2组患者均治疗4周,采用鼻部症状总评分(TNNS)、视觉模拟量表(VAS)评分、RQLQ评分、总IgE、IL-4水平和总有效率对临床疗效进行评价。结果治疗4周后2组患者TNNS、VAS、RQLQ评分及总IgE、IL-4值均明显降低(P<0.01),治疗组在改善VAS、RQLQ评分、IL-4水平方面均优于对照组(P<0.01),治疗组临床疗效和远期随访效果优于对照组(P<0.05~0.01)。结论刮痧配合氯雷他定是治疗变应性鼻炎的有效方法,有良好的远期效果。

OBJECTIVE To study the clinical effect of scraping therapy along meridian combined with loratadine in the treatment of persistent allergic rhinitis(PAR)caused by heat accumulation in lung meridian.METHODS Sixty patients with PAR caused by heat accumulation in lung meridian included in the affiliated hospital of Nanjing University of Chinese Medicine from March,2015 to September,2016 were selected and randomly divided into the loratadine control group,the scraping and loratadine combination group,30 cases in each group.Patients in both groups were treated for 4 weeks.Clinical curative effect was evaluated by total nasal symptoms scores(TNSS),visual analog scale(VAS),RQLQ score,total IgE,IL-4 level and total effective rate.RESULTS TNNS,VAS,RQLQ score,total IgE and IL-4 level all decreased in two groups after 4 weeks' treatment(P<0.01).The treatment group was better than the control group in improving VAS,RQLQ score and IL-4 level(P<0.01).And the treatment group was better than the control group in clinical effect and long-term follow-up effect(P<0.05~0.01).CONCLUSIONS Scraping and loratadine combination therapy is an effective treatment for allergic rhinitis and has satisfied long-term effect.