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康脉通预防骨科大手术术后下肢深静脉血栓形成的临床研究

Study on Kangmaitong in Prevention of Deep Venous Thrombosis After Large Orthopedic Surgery
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摘要 目的观察康脉通预防骨科大手术术后下肢深静脉血栓(DVT)形成的疗效及安全性。方法选取某院2016年3月~2017年3月行骨科大手术患者120例。随机分为康脉通组、低分子肝素组及利伐沙班组,每组40例。比较康脉通组与低分子肝素组、利伐沙班组下肢静脉血栓的发生率,术中、术后出血情况,以及D-二聚体、纤维蛋白原变化情况。结果康脉通组与低分子肝素组、利伐沙班组比较,术后下肢深静脉血栓发生率差异无统计学意义(P>0.05),无明显出血事件发生;术中、术后出血情况,以及D-二聚体、纤维蛋白原变化情况差异无统计学意义(P>0.05)。结论康脉通在预防骨科大手术术后下肢DVT形成方面具有良好的疗效及安全性。 OBJECTIVE To observe the effects of Kangmaitong in prevention of deep venous thrombosis (DVT) after large orthopedic surgery. METHODS 120 patients after large orthopedic surgery between March 2016 to March 2017 of a hospital were selected, they were divided into Kangmaitong group, Rivaroxaban group and low molecular weight heparin (LMWH) group. Compared the occurrence rate of DVT, bleeding and D-Dimer, fibrinogen before and after operation between Kangmaitong group with Rivaroxaban group and LMWH group. RESULTS The occurrence rate of DVT, bleeding and D-Dimer,fibrinogen before and after operation were no obviously change between Kangmaitong group with Rivaroxaban group and LMWH group (P 〉 0.05 ). No bleeding events occurred. CONCLUSION Kangmaitong can prevent DVT after large orthopedicsurgery effectively and safely.
出处 《今日药学》 CAS 2017年第10期692-695,共4页 Pharmacy Today
基金 江西省教育厅科学技术研究项目(150280) 江西省科技计划项目(20141BBG70055)
关键词 康脉通 骨科大手术 深静脉血栓 Kangmaitong large orthopedic surgery deep venous thrombosis
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