2014年广东省孕产妇HBV阳性检出情况空间聚集特征分析

Spatial clusters of hepatitis B surface antigen positive pregnant women in Guangdong in 2014

目的了解广东省孕产妇乙型肝炎(简称乙肝)病毒(HBV)阳性检出情况的空间聚集性分布,为广东省预防乙肝母婴传播项目工作提供改进依据。方法常规收集2014年广东省各级助产机构发现并上报的感染孕产妇信息,通过国家预防艾滋病、梅毒和乙肝母婴传播管理信息系统报告并收集相关数据,采用SaTScan进行空间扫描统计分析,运用ArcGis对孕产妇HBV抗体阳性检出率地区分布及空间扫描统计分析结果进行地图呈现。结果2014年广东省报告HBV感染孕产妇共计182 782例,孕产妇HBV阳性检出率达10.10%。空间扫描统计结果显示,2014年广东省存在三个有统计学意义的孕产妇HBV感染聚集区域(P<0.001)。一级聚集区域由茂名市、湛江市、阳江市和云浮市组成,其孕产妇HBV检出率为11.33%;二级聚集区域为梅州市,其孕产妇HBV检出率为12.12%;三级聚集区域由广州市和佛山市组成,其孕产妇HBV检出率为10.75%。结论空间扫描统计分析有助于发现HBV感染的高发聚集区域,广东省HBV感染孕产妇存在聚集性分布特征。

Objective To investigate the spatial aggregation of HBV positive rate among pregnant women in Guangdong province, so as to provide a reference in HBV prevention of mother-to-child transmission. Methods Data reported by all midwifery institutions at each level were collected from the national integrated PMTCT surveillance system. SaTScan software was employed to analyze the saptial aggregation, and ArcGis was used for map rendering. Results There were 182 782 HBV infected maternal in Guangdong in 2014, and the positive detection rate of women in pregnancy was 10.10%, concentrated in the three areas with the difference statistically significant （P〈 0. 001）. The first gathering area consisted of cities such as Maoming, Zhanjiang, Yangjiang and Yunfu, where the HBV positive detection rate was 11.33%. The second area was Meizhou city, with the HBV positive detection rate of 12.12% and the third area covered cities of Guangzhou and Foshan with the HBV positive rate of 10.75%. Conclusion Spatial scanning statistical analysis is conducive to discovery of high HBV incidence areas, and shows that there are distribution characteristics of aggregation of HBV infected maternal in Guangdong province.