血吸虫病小鼠动物模型在人体寄生虫学教学中的应用

Application of mouse model of schistosomiasis in the curriculum of human parasitology

为了加深学生对人体寄生虫学课程中血吸虫病内容的理解,探索行之有效的辅助教学手段将有助于提升教学效果。本文通过小鼠感染日本血吸虫建立血吸虫病动物模型,设计规范的教学内容,充分合理使用动物模型资源,在实习课堂上对日本血吸虫生活史主要发育阶段、寄生特征、小鼠血吸虫病模型的症状、重要脏器的病变特点和病理变化一一进行展示和解读,培养学生实践操作能力,应用动物模型来弥补理论课堂上抽象教学的不足,建立学生对血吸虫病的系统性认识,从而提升人体寄生虫学课程的教学质量,促进医学基础课程教育。

To strengthen the understanding of schistosomiasis in the curriculum of human parasitology, an effective and feasible method will benefit to the improvement of teaching quality. In this study, by constructing mouse model of schistosomiasis infected with Schitosoma japonicum, designing standard teaching contents, and fully exploring the resources of this animal model in the practice classes, we displayed and interpreted the morphology of key stages of Schitosoma in its life cycle, its parasitic features, the symptoms of schistosomiasis in mouse model, the pathological changes of affected organs. The mouse model of schistosomiasis applied in the practice classes would make up for the shortages left in the theory classes, push the students to form a comprehensive understanding to schistosomiasis, to enhance their operation ability, and therefore, would significantly elevate the teaching quality of human parasitol- ogy course and contribute to the promotion of basic medical education.