1,4-戊二烯-3-酮衍生物在农药创制中的应用进展

Research Progress of 1,4-Pentadien-3-one Derivatives in Development of Agrochemicals

1,4-戊二烯-3-酮衍生物作为一种重要的天然姜黄素衍生物,具有抗病毒、抑菌、杀虫、抗氧化、抗癌、消炎等较为广泛的生物活性,在医药和农药的创制中发挥着重要作用。综述了近年来1,4-戊二烯-3-酮衍生物在农药创制方面的研究进展,主要包括通过醚化和肟化来创制具有抗病毒、抑菌、杀虫等生物活性的活性药性分子,以期望对研究工作者有一定的启发。

1,4-Pentadien-3-one derivatives, which play an important role in the discovery of pharmaceuticals and agrochemicals, have broad spectrum of biological activities including antiviral, antimicrobial, insecticidal, antioxidant, antieancer, anti-inflammatory properties. 1,4-Pentadien-3-one derivatives with antiviral, antimicrobial, insecticidal activities in development for agrochemicals were reviewed according to etherification and oximation based on their structures, which could inspire the discovery and development for corresponding derivatives with potent bioactivities.