对乙酰氨基酚在硼掺杂金刚石薄膜电极上的电化学行为及测定

Electrochemical behavior and determination of paracetamol at boron-doped diamond electrodes

硼掺杂金刚石(BDD)薄膜电极是用于电化学分析的理想电极材料。采用循环伏安法研究了BDD电极上对乙酰氨基酚的电化学行为。研究发现,对乙酰氨基酚的氧化反应为不可逆电氧化反应,氧化峰电流与扫描速率的平方根成正比,受扩散控制。通过优化循环伏安测试参数建立了BDD电极上对乙酰氨基酚的测定方法,优化后测试参数为扫描速率10 mV/s,电压扫描范围为-1.0~2.0 V(vs.Ag/AgCl),扫描1次,扫描步长2.44 mV,得到氧化峰电流值与对乙酰氨基酚浓度在10.0~500.0 mg/L范围内呈线性关系,线性回归曲线为Y=1.279 34×10~6X+5.696 73,r=0.999 79。对本测定方法进行了精密度、稳定性和回收率的方法学考察,测定结果令人满意。

Boron-doped diamond( BDD) electrode is an ideal electrode material used in electrochemical analysis. The electrochemical behavior of paracetamol at BDD electrode was investigated by cyclic voltammetry. The results showed that the electrochemical oxidation of paracetamol was irreversible with oxidation peak current in proportion to the square root of the scan rate,which controlled by diffusion. The paracetamol determination at boron-doped diamond electrodes was established by optimization of cyclic voltammetry parameters with scan rate of 10 mV/s,voltage scan range of -1. 0 ~ 2. 0 V( vs. Ag/AgCl),1 times scan,scanning step of 2. 44 mV. The oxidation peak current was in proportional to paracetamol concentration at 10. 0 ~ 500. 0 mg/L. Linear curve was Y = 1. 279 34 × 10~6 X + 5. 696 73,r = 0. 999 79. The precision,stability and recovery test showed well results.