苯磺酸左旋氨氯地平在轻中度老年高血压治疗中对脉压的影响

The effect of levamlodipine besylate on pulse pressure in the treatment of mild to moderate senile hypertension

目的:探讨和分析苯磺酸左旋氨氯地平在老年轻中度高血压治疗过程中的应用效果。方法:收治轻中度高血压的老年患者100例,随机分两组。给予观察组患者苯磺酸左旋氨氯地平治疗,对照组患者给予苯磺酸氨氯地平治疗。对所有患者的血压进行监测,在治疗周期结束之后对两组患者的疗效进行对比。结果:观察组患者在治疗8周之后的总体有效率92%,高于对照组的80%;治疗结束后,观察组患者的舒张压和收缩压明显降低,差异有统计学意义(P<0.05)。结论:在轻中度高血压老年患者的临床治疗中使用苯磺酸左旋氨氯地平,能有效控制血压,对脉压产生的影响也较小,还能对心脏功能进行保护,所产生的不良反应非常少。

Objective：To investigate and analyze the effect of levamlodipine besylate on pulse pressure in the treatment of mild to moderate senile hypertension.Methods：100 eldly patients with mild to moderate senile hypertension were selected,they were randomly divided into the two groups,patients in the treatment group were treated with levamlodipine besylate treatment,the control group was treated with amlodipine besylate,the blood pressure of all the patients was monitored and the efficacy of the two groups was compared after the end of the treatment cycle.Results：The total effective rate of the observation group after 8 weeks of treatment was 92%,which was higher than 80% of the control group.After treatment,the diastolic blood pressure and systolic blood pressure in the observation group were significantly decreased,the differences were statistically significant（P〈0.05）.Conclusion：In the treatment of elderly patients with mild to moderate hypertension,the use of levamlodipine besylate can effectively control blood pressure,and has less influence on pulse pressure,it also protects the heart and produces fewer side effects.