卡前列素氨丁三醇治疗产后出血的临床疗效分析

Clinical effect analysis of carboprost tromethamine in the treatment of postpartum hemorrhage

目的分析卡前列素氨丁三醇治疗产后出血的临床疗效。方法选择我院2015年9月至2016年7月收治的产后出血产妇64例,依据治疗方法将其分为两组。将接受缩宫素治疗的32例产妇作为对照组,接受卡前列素氨丁三醇治疗的32例产妇作为研究组,比较两组产妇治疗效果。结果两组产妇经不同方法治疗后,研究组产妇的治疗总有效率(96.9%)和子宫收缩率(93.8%)明显高于对照组(78.2%、71.9%)(P<0.05)。研究组产后2 h出血量为(273.3±10.4)mL,止血时间为(15.2±3.3)min,产后出血发生率为3.1%,明显低于对照组的(547.3±14.6)mL、(35.3±7.4)min、25.0%(P<0.05)。研究组不良反应总发生率(6.2%)明显低于对照组(28.0%)(P<0.05)。结论产后出血予以卡前列素氨丁三醇治疗,效果理想,不仅可以有效控制产妇的出血情况,而且具有较高的安全性,可在临床上进一步实践。

Objective To analyze the clinical efficacy of carboprosl Iromelhamine in the Irealmenl of poslparlum hemorrhage. Methods Sixty-four cases of maternals with postpartum hemorrhage admitted in our hospital from September 2015 to July 2016 were selected and divided into two groups according to different treatment methods. Thirty-two cases of maternals who received uterine contraction treatment were classified as reference group, and thirty-two cases of maternals who received carboprost tromethamine were classified as study group. The treatment effects were compared between the two groups. Results After treatment with different methods, the total effective rate of the study group was 96.9%, and the uterine contraction rate was 93.9%, which were higher than 78.2%, 71.9% of the reference group （ P〈0.05）. In the study group, the 2 h postpartum bleeding loss volume, hemostasis time, incidence of postpartum hemorrhage were （273.3±10.4） mL,（15.2±3.3）minand3.1% respectively, whichwerelowerthan（547.3±14.6）mL,（35.3±7.4）min,25.0%inthecontrol group respectively （P 〈0.05）. The overall incidence of adverse reactions in the study group was 6.2% , which was significantly lower than 28.0% in the control group （ P〈0.05）. Conclusion The carboprost tromethamine in the treatment of postpartum hemorrhage has ideal effect, which can effectively control the patient＇s bleeding conditions with a high safety, and can be further practiced in clinic.