摘要
目的观察针刺对痰湿壅盛型Ⅰ级原发性高血压患者血管炎性因子超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)水平的影响,探讨炎性因子与血压变化的关系。方法将60例痰湿壅盛型Ⅰ级原发性高血压患者随机分为治疗组和对照组,每组30例。治疗组采用辨证取穴针刺治疗,对照组采用非经非穴针刺治疗,共治疗18次。比较两组治疗前后24 h动态血压及血清hs-CRP、IL-6水平的变化情况。结果治疗组治疗后24 h平均SBP、DBP与同组治疗前比较,差异均具有统计学意义(P<0.01)。两组治疗后24 h平均SBP、DBP比较,差异均具有统计学意义(P<0.05)。两组治疗后血清hs-CRP及IL-6水平虽有所下降,但与同组治疗前比较,差异均无统计学意义(P>0.05)。结论针刺是一种治疗痰湿壅盛型原发性高血压的有效方法,其机制可能与血清hs-CRP、IL-6炎症因子水平的下降有关。
Objective To observe the effect of acupuncture on the levels of hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) in patients with grade Ⅰ primary hypertension due to excessive retention of dampness-heat, and discuss the relationship between inflammatory factors and the change of blood pressure. Method Sixty patients with grade Ⅰ primary hypertension due to excessive retention of dampness-heat were randomized into a treatment group and a control group, 30 cases each. The treatment group was intervened by acupuncture with points selected based on syndrome differentiation, and the control group was treated with acupuncture at non-meridian points, for 18 sessions in total. The 24-hour ambulatory blood pressure, and serum hs-CRP and IL-6 levels were compared before and after the treatment. Result After the treatment, the 24-hour systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly changed in the treatment group (P〈0.01). There were significant differences in comparing the 24-hour SBP and DBP between the two groups after the treatment (P〈0.05). The serum hs-CRP and IL-6 levels dropped after the treatment in both groups but without statistical significances (P〉0.05). Conclusion Acupuncture is an effective approach in treating primary hypertension due to excessive retention of dampness-heat, and its action mechanism may be associated with the decrease of serum hs-CRP and IL-6 levels.
作者
刘梅芳
施静
LIU Mei-fang;SHI Jing(Yunnan Provincial Hospital of Traditional Chinese Medicine,Kunming 650021,China)
出处
《上海针灸杂志》
2017年第11期1295-1298,共4页
Shanghai Journal of Acupuncture and Moxibustion
基金
云南省针灸研究中心课题(2014NS320)
关键词
针刺疗法
高血压
痰湿壅盛
炎症因子
超敏C反应蛋白
白介素-6
Acupuncture therapy
Hypertension
Excessive retention of dampness-heat
Inflammatory factors
hs-CRP
IL-6