射干麻黄汤加减治疗小儿哮喘的临床疗效及安全性研究

Clinical effect and safety of Shegan Mahuang decoction in the treatment of infantile asthma

目的分析和研究射干麻黄汤加减治疗小儿哮喘的临床疗效及安全性。方法选择本院在2013年11月至2016年8月收治的79例小儿哮喘患儿为研究对象,将其分成A组和B组,分别为44例和35例。B组患儿采用常规治疗,A组患儿在常规治疗基础上加用射干麻黄汤加减治疗。对比两组患儿的临床疗效和不良反应发生率。结果 A组患儿的治疗总有效率为95.45%,B组患儿的治疗总有效率为85.71%,A组明显高于B组,差异有统计学意义(P<0.05)。A组患儿的不良反应发生率为6.82%,B组患儿的不良反应发生率为37.14%,A组明显低于B组,差异有统计学意义(P<0.05)。结论小儿哮喘采用射干麻黄汤加减治疗具有显著的临床疗效且不良反应发生率低,安全性高,可在临床中推广应用。

Objective To analyze and study the clinical effect and safely of Shegan Mahuang decoclion in the Irealmenl of infantile asthma. Methods A lolal of 79 children with infantile asthma admitted in our hospilal from November 2013 lo Augusl 2016 were selecled as lhe research objecls. All lhe children were divided inlo group A （ n=44） and group B （ n=35）. Group B received routine treatment, while group A accepted Shegan Mahuang decoclion on lhe basis of routine treatment. The clinical effect and lhe incidence rale of adverse reactions of lhe lwo groups were compared. Results The lolal effective rale of lhe group A was 95.45%, which was higher than 85.71% of lhe group B, lhe difference was slalislically significant （ P〈 0.05）. The incidence rale of adverse reactions in group A was 6.82%, which was lower than 37.14% of lhe group B, lhe difference was slalislically significant （P 〈0.05）. Conclusion Shegan Mahuang decoclion in lhe treatment of infantile asthma has significant clinical effect, low incidence rale of adverse reactions and high safely, which can be applied and popularized in clinic.