预防性使用抗生素对胎膜早破产妇的母婴预后的影响

Effect of prophylactic use of antibiotics on maternal and neonatal prognosis in premature rupture of membranes

目的研究探讨预防性使用抗生素的胎膜早破产妇的母婴预后情况。方法选取本院2015年4月至2017年1月收治的胎膜早破产妇40例,依据产妇抗生素用药意愿进行分组观察,观察组20例,针对胎膜早破产妇病情状态给予预防性抗生素治疗,对照组20例,未实施抗生素用药,观察两组母婴预后效果。结果观察组产妇在剖宫产率、产后感染、绒毛膜炎以及胎儿窘迫、新生儿吸入性肺炎发生率显著低于对照组,差异有统计学意义(P<0.05)。结论采取预防性用药方式进行胎膜早破的期待治疗,可延长胎儿妊娠发育时间,降低宫内感染率,降低新生儿并发症,改善治疗效果。

Objective To study the effect of prophylactic use of antibiotics on maternal and neonatal prognosis in pre-mature rupture of membranes. Methods Forty cases of fetal premature rupture of membranes patients from April 2015 to January 2017 in our hospital were selected. According to the willingness of maternal antibiotics, 20 cases were grouped into the observation group and given preventive antibiotic treatment according to the states of illness, the control group of 20 cases did not receive the mplementation of antibiotics. The prognosis effect of maternal and fetal in the two groups was observed. Results The incidences of cesarean section, postpartum infection, choriocarcinoma, fetal distress,neonatal inhalation pneumonia in the observation group were significantly lower than those in the control group, and the differences were statistically significant(P<0.05). Conclusion The prophylactic treatment in fetal premature rupture can prolong fetal pregnancy development time, reduce intrauterine infection rate and neonatal complications and improve the therapeutic effect.