磁敏感加权成像在坏死性脑胶质瘤与脑脓肿鉴别诊断中的价值

The value of susceptibility weighted imaging in the identification of necrotic glioblastomas and brain abscesses

目的探讨磁敏感加权成像(susceptibility weighted imaging,SWI)在坏死性脑胶质瘤与脑脓肿鉴别诊断中的价值。材料与方法回顾性分析23例坏死性脑胶质瘤患者和16例脑脓肿患者,所有患者均在3.0 T磁共振成像仪上进行了常规磁共振成像和SWI,通过是否检出病灶内磁敏感信号(intralesional susceptibility signal,ILSS)来评价SWI对鉴别坏死性脑胶质瘤与脑脓肿的价值。结果 23例坏死性胶质瘤患者中,22例患者检出ILSS(95.7%),16例脑脓肿患者中6例检出ILSS(37.5%),利用ILSS区分坏死性胶质瘤和脑脓肿敏感性96%,特异性63%,坏死性脑胶质瘤患者ILSS检出率显著大于脑脓肿患者(OR=36.67,P=0.002)。结论 SWI在坏死性脑胶质瘤与脑脓肿的鉴别诊断中具有重要价值。

Objective To investigate the value of susceptibility weighted imaging （SWI） in differentiating the necrotic glioblastomas and brain abscesses. Materials and Methods： Twenty-three patients with necrotic glioblastomas and 16 patients with brain abscesses were retrospectively analyzed. All patients underwent conventional MRI and SWI on a 3.0 T MR unit. To evaluate the value of SWI in differentiating the necrotic glioblastomas and brain abscesses by detecting the intralesional susceptibility signal （ILSS）. Results： Twenty-two （95.7%） of 23 patients with necrotic glioblastomas were detected with ILSS. Six （37.5%） of 16 patients with brain abscesses were detected with ILSS. The sensitivity of ILSS in differentiating necrotic glioblastomas and brain abscesses patients was 96% and the specifcity was 63%. The detection rate of ILSS in patients with necrotic glioblastomas was higher than that in patients with brain abscesses （OR=36.67, P=0.002）. Conclusion： SWI has great value in differentiating the necrotic glioblastomas and brain abscesses.