磁共振扩散加权成像的表观扩散系数值在鉴别均质良恶性甲状腺微小结节中的作用

Differentially diagnostic value of ADC values in diagnosing homogeneous benign and malignancy of thyroid nodules

目的探究磁共振扩散加权成像(diffusion weighted imaging,DWI)中的表观扩散系数(apparent diffusion coefficient,ADC)对均质甲状腺微小结节的鉴别诊断价值,提高对均质甲状腺微小结节的影像学鉴别诊断水平。材料与方法选取河北医科大学第二医院经手术病理证实的162例均质甲状腺微小结节患者,共226个病灶进行磁共振常规扫描和DWI检查。将所得全部病灶的影像学数据进行统计学分析。结果均质甲状腺微小结节病灶在DWI检查中,设定不同b值所得出的ADC值有所不同;取b值为300 s/mm^2、500 s/mm^2和800 s/mm^2时,DWI扫描所得出的ADC值良性和恶性结节之间的差异有统计学意义(P<0.05);而在b值为0 s/mm^2和1000 s/mm^2时,DWI扫描所得出的ADC值良性和恶性结节之间的差异无统计学意义(P>0.05)。结论 ADC值对均质甲状腺微小结节良恶性的鉴别诊断具有一定意义。

Objective To investigate the differential diagnostic value of apparent diffusion coeffcient （ADC） in diffuse weighted imaging （DWI） in the diagnosis of minimally invasive thyroid nodules and to improve the homogeneous thyroid nodules of the differential diagnosis of imaging. Materials and Methods： Select 162 cases confrmed by surgery pathology in the second hospital of Hebei medical university homogeneous patients with thyroid nodules, a total of 226 lesions on magnetic resonance scan and conventional DWI examination used the proceeds of all lesions imaging data for statistical analysis. Results： Homogeneous thyroid nodule in DWI examination, setting different b factors of ADC values obtained ADC values were different. Take b factor of 300, 500 and 800 s/mm2, the difference of ADC values obtained from DWI scan between benign and malignant nodules was statistically significant （P〈0.05）. Take b factor of 0 and 1000 s/mm2, the difference of ADC values obtained from DWI scan between benign and malignant nodules was not statistically signifcant （P〉0.05）. Conclusions： ADC value is of signifcance to the differential diagnosis of homogeneous thyroid nodules.