磁共振体素内不相干运动在肿瘤中的研究进展

Research progress of intravoxel incoherent motion in tumor

磁共振体素内不相干运动(intravoxel incoherent motion,IVIM)是在扩散加权成像(diffusional weight imaging,DWI)基础之上,通过双指数模型得出相关参数,在不使用对比剂的情况下,同时反映组织内水分子自由扩散和微循环血流灌注信息。近年来,IVIM逐渐应用于各系统疾病研究,尤其在脑、肝脏等肿瘤中取得了初步成果,展现出良好的临床价值。作者就IVIM成像原理、肿瘤中的应用进展予以综述。

Intravoxel incoherent motion （IVIM） is based on diffusional weight imaging （DWI）, IVIM relevant parameters are obtained from bi-exponential model, they can represent pure molecular diffusion and incoherent microcirculation within the voxel at the same time in the tissue without the use of contrast agents. In recent years, IVIM gradually applied to diseases of different systems, especially in the cancer of brain and liver had achieved some initial results, which displayed excellent clinical value. This article proposed to summary technical principles and application advances in tumors of IVIM.