补阳还五汤加减治疗对气虚血瘀型缺血性卒中患者血脂及炎性因子水平的影响

Effect of Modified Buyang Huanwu Decoction Treatment on Blood Lipid and Inflammatory Factor level in Patient with Qixu Xueyu Type Ischemic Stroke

目的:分析补阳还五汤加减治疗对气虚血瘀型缺血性卒中患者血脂及炎性因子水平的影响。方法:气虚血瘀型缺血性脑卒中患者70例,随机分为2组,各35例。对照组采用常规治疗,观察组在对照组基础上加用补阳还五汤,对比2组治疗前后血脂及炎性因子水平、症状积分。结果:治疗后,观察组TC、TG,LDL-C、hs-CRP、MMP-9水平低于对照组,观察组症状积分为(6.22±1.54)分低于对照组(7.49±1.83)分,HDL-C水平高于对照组,差异有统计学意义(P<0.05)。结论:补阳还五汤加减治疗可有效降低气虚血瘀型缺血性卒中患者血脂及炎性因子水平,恢复动脉血管弹性,减少动脉粥样斑块发生,在临床应用中值得推广。

Objective： To evaluate the effect of Buyang Huanwu decoction on blood lipid and inflammatory factors in patients with deficiency of Qi deficiency and blood stasis syndrome. Methods： 70 patients with ischemic stroke were randomly divided into two groups： 35 cases. The control group was treated with conventional therapy. The observation group was treated with Buyang Huanwu decoction on the basis of the control group. The levels of blood lipid and inflammatory factors were compared before and after treatment. Results： After treatment, the levels of TC, TG, LDL-C, hs-CRP and MMP-9 in the observation group were lower than those in the control group （6.22 ± 1.54） and the control group （7.49 ± 1.83） HDL-C level was higher than the control group, the difference was statistically significant （P〈0.05）. Conclusion： Buyang Huanwu decoction can effectively reduce the levels of blood lipid and inflammatory factors in patients with ischemic stroke of qi deficiency and blood stasis, restore arterial elasticity and reduce the occurrence of atherosclerotic plaque. It is worthy to be popularized in clinical application.