自拟伤科A配合PFNA内固定治疗股骨粗隆间骨折临床研究

The Clinical Research of Self-made Traumatologic Prescription A in the Treatment of Femoral Intertrochanteric Fractures with PFNA Internal Fixation

目的:探讨院内协定方伤科A配合PFNA内固定治疗骨质疏松性股骨粗隆间骨折的临床疗效。方法:将60例骨质疏松性股骨粗隆间骨折患者分为治疗组和对照组各30例,在PFNA内固定微创治疗基础上,治疗组给予中药伤科A汤剂+仙灵骨葆胶囊治疗,对照组给予仙灵骨葆胶囊治疗,疗程均为3个月。观察2组患者术后血红蛋白(Hb)、C反应蛋白(CRP)和血沉(ESR)水平,同时观察2组患者髋关节Harris评分和患髋疼痛视觉模拟评分(VAS评分)。结果:60例入选病例均获得完整随访,治疗组病患血红蛋白、C反应蛋白及血沉方面均优于对照组,差异有统计学意义(P<0.05);术后第2天至第6天内治疗组VAS评分好于对照组,差异有统计学意义(P<0.05),术后一周后无明显统计学意义(P>0.05),术后第2周至1月内治疗组Harris评分优于对照组,差异有统计学意义(P<0.05),后期无明显统计学意义(P>0.05)。结论:伤科A可促进患者术后血红蛋白、C反应蛋白、血沉的恢复,说明伤科A在一定程度上可促进股骨粗隆间骨折病患术后血红蛋白及炎症指标的恢复,减轻炎症反应,缓解疼痛,改善髋关节功能,从而促进患者机能的恢复,临床使用可取得更加满意的疗效。

Objective： To investigate the clinical efficacy of self-made traumatologic prescription A combine with PFNA internal fixation in the treatment of osteoporotic intertrochanteric fractures of the femur. Methods： Sixty patients with osteoporotic intertrochanteric fractures were divided into treatment group and control group. Base on the PFNA internal fixation and minimally invasive treatment, the treatment group given self-made traumatologic prescription A＋Xianling Gubao capsule treatment, the control group given Xianling Gubao capsule treatment, treatment course were 3 months. The levels of hemoglobin （Hb）, C-reactive protein （CRP） and ESR in the two groups were observed. The Harris score and the hip pain visual analogue scale （VAS score） were observed. Results： 60 cases were completely followed up. The hemoglobin, C-reactive protein and erythrocyte sedimentation rate in the treatment group were better than those in the control group （P〈0.05）. The VAS score of the treatment group was better than that of the control group from day 2 to day 6, the difference was statistically significant （P〈0.05）. There was no statistically significant difference between one week after operation （P〉0.05）. The Harris score of the treatment group was better than that of the control group from the second week to the last month （P〈0.05）. There was no significant statistical significance at the later stage （P〉0.05）. Conclusion： The injury A can promote the recovery of hemoglobin, C-reactive protein and erythrocyte after operation. It shows that the injury A can promote the recovery of hemoglobin and inflammation index in the patients with intertrochanteric fractures, reduce the inflammatory reaction, Relieve pain, improve hip function, thereby promoting the recovery of patient function. Clinical use can achieve a more satisfactory effect.