刘振寰经验方治疗注意力缺陷多动障碍患儿的SNAP-Ⅳ评估分析

Curative Effect of Experienced Recipe Prescribed by Professor LIU Zhen-Huan for Attention Deficit Hyperactivity Disorder Children Analyzed by SNAP-Ⅳ Rating Scale

【目的】通过SNAP-Ⅳ评定量表评价刘振寰教授经验方消惊汤加减治疗肝肾阴虚型注意力缺陷多动障碍(ADHD)患儿的临床疗效。【方法】采用随机对照的试验方法,将60例患儿随机分为中药组及对照组,每组各30例。中药组给予刘振寰教授经验方消惊汤加减口服治疗,对照组给予哌甲酯片口服治疗。比较2组患儿治疗4周后SNAP-Ⅳ评定量表各分量表分值变化情况及其临床缓解率情况。【结果】(1)治疗4周后,2组患儿SNAP-Ⅳ评定量表中注意力不集中、多动—冲动分量表评估分值均较治疗前明显改善(P<0.01),且中药组对患儿注意力不集中、多动—冲动分量表评估分值的改善作用均明显优于对照组(P<0.05)。(2)中药组临床缓解率为60.0%,对照组为33.3%,中药组的临床缓解率明显优于对照组,差异有统计学意义(P<0.05)。【结论】刘振寰教授经验方消惊汤加减治疗肝肾阴虚型注意力缺陷多动障碍患儿疗效显著。

Objective To evaluate the clinical curative effect of applying the modified Xiaojing Decoction, an experienced recipe prescribed by Professor LIU Zhen-Huan,for the treatment of attention deficit hyperactivity disorder（ADHD）children with liver-kidney yin deficiency by using the Swanson,Nolan,and Pelham,VersionⅣ（SNAP-Ⅳ） rating scale. Methods By the methods of randomized controlled trial, 60 cases of ADHD children were randomly divided into Chinese medicine group and control group,30 cases in each group. Chinese medicine group was treated with Xiaojing Decoction orally, and the control group was given Methylphenidate Tablets orally. After treatment for 4 weeks, the scores of subscales of SNAP-Ⅳ rating scale and clinical remission rate of the two groups were compared. Results（1）After treatment for 4 weeks,the scores of attentiondeficit subscale and hyperactivity-impulsivity subscale of the two groups were much improved（P〈0.01 compared with those before treatment）,and the improvement in Chinese medicine group was superior to that in the control group（P〈0.05）.（2）Clinical remission rate of Chinese medicine group arrived to 60.0%,and that of the control group was 33.3%,the difference being significant（P〈0.05）. Conclusion The modified Xiaojing Decoction,an experienced recipe prescribed by Professor LIU Zhen-Huan,exerts certain therapeutic effect for the treatment of ADHD children with liver-kidney yin deficiency.