医用生物胶体分散剂联合雌三醇软膏阴道上药在子宫切除术后对阴道残端愈合的影响

Effect of Medical Biocolloid Dispersing Agent and Vaginal Dressing of Estriol Cream on the Vaginal Residual End Healing after Hysterectomy

目的探讨生物胶联合雌三醇软膏在子宫全切术后阴道残端愈合的影响。方法将该院2015年9月—2017年1月年龄在46~65岁之间150例,行子宫全切术患者术前术后阴道应用医用生物胶体分散剂联合雌三醇软膏作为观察组,术前术后应用0.5%碘伏阴道擦洗作为对照组,术后5 d及术后1月对两组患者阴道分泌物清洁度异常、流血、阴道残端息肉(肉芽)形成情况等指标进行评判。结果观察组术后5 d阴道分泌物清洁度异常、p H值阳性率、细菌性阴道病发生率、阴道残端流血及肉芽形成发生率、阴道用药时疼痛不适感发生率分别为6.7%、9.3%、6.7%、8.0%、8.0%,与对照组相比差异无统计学意义(P>0.05);观察组术后1个月阴道分泌物清洁度异常、p H值阳性率、细菌性阴道病发生率、阴道残端流血及肉芽形成发生率、阴道用药时疼痛不适感发生率分别为8.0%、6.7%、5.3%、6.7%、6.7%,明显优于对照组(P<0.05)。结论对于行子宫全切卵巢功能减退患者术前术后应用医用生物胶体分散剂喷洒外阴阴道局部涂抹雌三软膏取得良好的效果。

Objective To study the effect of medical biocolloid dispersing agent and vaginal dressing of estriol cream on the vaginal residual end healing after hysterectomy. Methods 150 cases of patients aged between 46 and 65 years old from September 2015 to January 2017 were selected, the observation group were treated with medical biocolloid dispersing agent and vaginal dressing of estriol cream before and after operation, while the control group applied the0.5% iodophor vaginal cleaning before and after operation, and the vaginal fluid cleanliness abnormality, bleeding, formation of vagina remnant end polyp（granulation） were determined after 5 d and 1-month operation. Results The vaginal fluid cleanliness abnormality rate, p H value positive rate, incidence rate of bacterial vaginal disease, incidence rate of vaginal stump bleeding and incidence rate of granulation and incidence rate of pains discomfort of vaginal at vaginal medication were respectively 6.7%,9.3%,6.7%,8.0%,8.0%, and the differences between the two groups were statistically significant（P〉0.05） and the vaginal fluid cleanliness abnormality, p H value positive rate, incidence rate of bacterial vaginal disease, incidence rate of vaginal stump bleeding and granulation formation and incidence rate of pain discomfort at vaginal medication were respectively 8.0%,6.7%,5.3%,6.7%,6.7%, which were obviously better than those in the control group（P〈0.05）. Conclusion The application effect of medical biocolloid dispersing agent and vaginal dressing of estriol cream in patients with total hysterectomy hyop-ovarianism before and after operation is good.