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氯吡格雷、替格瑞洛对老年不稳定型心绞痛患者炎症反应的影响 被引量:13

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摘要 目的探讨氯吡格雷、替格瑞洛对老年不稳定型心绞痛患者的疗效及对炎症反应的影响。方法将老年不稳定型心绞痛患者116例随机分为两组,均行常规治疗,对照组加用氯吡格雷,观察组加用替格瑞洛,比较两组治疗情况及炎症指标水平。结果治疗3个月时两组心绞痛发作频率、每次发作持续时间、白细胞介素(IL)-6、超敏C反应蛋白(hs-CRP)均明显低于治疗前(P<0.05),且观察组各指标明显低于对照组(P<0.05),观察组总有效率明显高于对照组(P<0.05)。两组均无重大不良心血管事件发生,不良反应发生率差异不显著(P>0.05)。结论氯吡格雷、替格瑞洛均可减轻老年不稳定型心绞痛患者的炎症反应,替格瑞洛的效果更为明显,两种药物安全性相当。
出处 《中国老年学杂志》 CAS 北大核心 2017年第21期5313-5315,共3页 Chinese Journal of Gerontology
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