多肽类化合物在颅脑创伤中的研究进展

Research progress of peptide compounds in traumatic brain injury

颅脑创伤每年在全球造成严重的伤亡,至今研究者们依然没有找到有效的临床治疗药物。肽类物质以其安全、易耐受等优势逐渐成为研究开发的热点。对多肽类化合物在颅脑创伤中的神经保护和抗炎作用进行综述。

Traumatic brain injuries （TBI） have caused severe injuries and deaths all over the world , but so far research-ers have not found an effective drug in treating TBI on clinic . However , peptides have gradually been in a hot research with its advantages which include safety and tolerance etc . The neuroprotective and anti-inflammatory effects of several peptide com - pounds in traumatic brain injury are reviewed in this paper .