小儿柴桂退热颗粒辅助治疗儿童上呼吸道感染临床观察

Clinical Observation of Adjuvant Treatment of Xiao'er Chaigui Tuire Granule in Treating Upper Respiratory Tract Infection in Children

目的:观察小儿柴桂退热颗粒辅助治疗儿童上呼吸道感染的临床疗效,及对患儿血清超敏C-反应蛋白(hs-CRP)、中性粒细胞百分比(GR)的影响。方法:选取116例上呼吸道感染患儿,按随机数字表法分为治疗组与对照组,每组58例。2组均给予抗炎、抗病毒等常规对症治疗,治疗组在此基础上加用小儿柴桂退热颗粒。评估临床疗效,观察治疗前后患儿hs-CRP及GR的变化。结果:治疗组总有效率94.83%,对照组总有效率75.86%。2组比较,差异有统计学意义(P<0.05)。治疗组退热时间、止涕时间均短于对照组,差异均有统计学意义(P<0.05)。2组咽部红肿消退时间比较,差异无统计学意义(P>0.05)。治疗后,2组hs-CRP水平及GR均较治疗前下降,差异均有统计学意义(P<0.05);治疗组hs-CRP水平及GR均比对照组下降更明显,差异均有统计学意义(P<0.05)。结论:采用小儿柴桂退热颗粒辅助治疗儿童上呼吸道感染,可显著改善患儿的临床症状、体征,提高治疗效果。

Adjective.. To observe clinical effect of adjuvant treatment of Xiao＇er Chaigui tuire granule in treating upper respiratory tract infection in children, and its effect on high sensitive C-reactive protein（hs-CRP） and neutrophil granulocyte ratio（GR）. Methods： Selected 116 children with upper respiratory tract infection, and divided them into the treatment group and the control group according to the random table method, 58 cases in each. Both groups were given antibiotics and antiviral agents, and the treatment group was given Xiao＇er Chaigui Tuire granule based on the routine treatment. Evaluated clinical effect and observed change of hs-CRP and GR in patients before and after treatment. Results= The total effective rate was 94.83% in the treatment group and was 75.86% in the control group, the difference being significant （P 〈0.05）. Defervescence time, time of nasal discharge stopped in the treatment group were shorter than those of the control group（P〈 0.05）. Compared time of pharyngeal redness and swelling fadeaway of the two groups, there was no significant difference （P 〉0.05）. After treatment, hs-CRP levels and GR of both groups were all lower than those before treatment （P 〈0.05）. Decrease of hs-CRP levels and GR of the treatment group were more obvions than those of the control group（P 〈0.05）. Conclusion： Adjuvant treatment of Xiao＇er Chaigui tuire granule can effectively improve clinical symptoms and body signs of the patients and curative effect in treating upper respiratory tract infection in children.